(Secobarbital Sodium) Capsules, USP

Rx Only



Seconal Sodium® is a barbiturate derivative. Barbiturates are non-selective central nervous system (CNS) depressants that are primarily used as sedative hypnotics.

As a barbiturate, Seconal Sodium works by depressing the central nervous system (sensory cortex), causing mild sedation, drowsiness or sleep.

Seconal Sodium is classified as a short-acting barbiturate when taken orally. Its onset of action is 10-15 minutes and duration of effect ranges from three to four hours.



Seconal Sodium is indicated as a hypnotic for the short-term treatment of insomnia (for up to two weeks) and as a preanesthetic (sedative) before surgery.


Side Effects

Seconal Sodium is contraindicated in patients who are hypersensitive to barbiturates; patients with a history of manifest or latent porphyria; marked liver impairment or respiratory disease. Barbiturates may be habit forming. Tolerance, psychological and physical dependence may occur with continued use. Allergic reaction may occur. Other serious side effects may include getting out of bed while not fully awake and doing an activity that you do not know you are doing, abnormal thoughts and behavior, memory loss, and anxiety. Common side effects include drowsiness, headache, fatigue, dizziness, dry mouth and upset stomach. The most commonly observed adverse event associated with Seconal Sodium use is somnolence (drowsiness), estimated to occur at a rate of 1 to 3 patients per 100.


How Supplied

Seconal Sodium is available in 100 mg capsules.




reader Full Prescribing Information >

reader Seconal Sodium ® Medication Guide >